A simple and effective 1,2,3-triazole based "turn-on" fluorescence sensor for the detection of anions

Debanjana Ghosh, Shannon Rhodes, Karena Hawkins, Domonique Winder, Austin Atkinson, Marshall Ming, Clifford Padgett, Jeffery A. Orvis, Karelle Aiken, Shainaz M. Landge

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

A novel and effective 1,2,3-triazole based fluorescence chemosensor has been synthesized for the specific detection of anions in homogeneous medium. Notably, the molecule, synthesized in one step using "Click chemistry", is a simple 1,4-diaryl-1,2,3-triazole, containing a phenol moiety. The probe displayed the strongest response to fluoride ion through the "turn-on" fluorescence sensing mechanism when screened for selectivity and sensitivity against a series of anions (F-, Cl-, Br-, I-, H2PO4-, ClO-, OAc-, BF4-). Fluorescence spectroscopy and Nuclear Magnetic Resonance Spectroscopy (NMR) studies substantiate 1:1 stoichiometry between the probe and fluoride anion. Kinetic studies and the single crystal X-ray spectroscopic evidence revealed the binding interaction occurs with the phenolic group and the anion.

Original languageEnglish
Pages (from-to)295-303
Number of pages9
JournalNew Journal of Chemistry
Volume39
Issue number1
DOIs
StatePublished - Jan 1 2015

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