A viral disease that damages the immunity conferred by different viral diseases or vaccination

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Abstract

In this paper we modify a standard SIR model used to study the spread of some diseases by incorporating a disease that destroys the immunity that is conferred by having one of the other diseases or being vaccinated against the disease. A specific biological example of this occurs with measles. Studies of recent measles’ patients has shown that many patients have lost some (or all) of their immunity to other diseases from which they were previously protected. In the future, models like those developed here might be helpful in understanding how viruses that affect multiple organ systems can impact the effect the disease has on at risk populations.

Original languageEnglish
Article number808
JournalMathematics
Volume9
Issue number8
DOIs
StatePublished - Apr 2 2021

Keywords

  • Basic reproductive ratio
  • Herd immunity
  • Immunity
  • Measles
  • SIR
  • SIS

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