Botulinum Toxin A for the Treatment of Cervical Dystonia

Kelly L. Sullivan, Theresa A. Zesiewicz, William Stamey, Robert A. Hauser

Research output: Contribution to journalArticlepeer-review

Abstract

Idiopathic cervical dystonia (ICD) is the most common adult-onset focal dystonia. It is characterised by relatively sustained, involuntary contractions of neck muscles. Injections of botulinum toxin (BTX)-A are safe and effective for the treatment of ICD, and have substantially improved its treatment. BTX-A is manufactured by Allergan Pharmaceuticals in the US and Ireland, and is distributed as Botox®. In Europe, BTX-A is manufactured and distributed by Ipsen Pharmaceuticals as Dysport®. Success rates for BTX-A injections for ICD ranges 64 – 90%, with 76 – 93% of injected patients experiencing pain reduction. Side effects are generally mild and include dysphagia and neck weakness.
Original languageAmerican English
JournalExpert Opinion on Pharmacotherapy
Volume5
StatePublished - Feb 25 2005

Keywords

  • Botox
  • Botulinum Toxin A
  • Cervical Dystonia
  • Dysport
  • Treatment

DC Disciplines

  • Public Health

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