Chloroacetamidine Based Inhibitors and Activity Based Probes for the Protein Arginine Methytransferases

Paul R. Thompson; Tanesha Osborne; Obiamaka Obianyo; Corey P. Causey

Chloroacetamidine Based Inhibitors and Activity Based Probes for the Protein Arginine Methytransferases

Paul R. Thompson
, Tanesha Osborne
, Obiamaka Obianyo
, Corey P. Causey

Biochemistry, Chemistry & Physics

University of South Carolina

Research output: Other contribution › Other

Abstract

U.S. Patent application, Serial No. 12 / 637,223.

In accordance with certain embodiments of the present disclosure, a protein arginine methyltransferase inhibitor is provided. The inhibitor comprises an amino acid peptide joined to a chloroacetamidine warhead.

Original language	American English
State	Published - 2010

Disciplines

Physical Sciences and Mathematics
Chemistry

Cite this

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title = "Chloroacetamidine Based Inhibitors and Activity Based Probes for the Protein Arginine Methytransferases",

abstract = " U.S. Patent application, Serial No. 12 / 637,223. In accordance with certain embodiments of the present disclosure, a protein arginine methyltransferase inhibitor is provided. The inhibitor comprises an amino acid peptide joined to a chloroacetamidine warhead. ",

author = "Thompson, \{Paul R.\} and Tanesha Osborne and Obiamaka Obianyo and Causey, \{Corey P.\}",

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T1 - Chloroacetamidine Based Inhibitors and Activity Based Probes for the Protein Arginine Methytransferases

AU - Thompson, Paul R.

AU - Osborne, Tanesha

AU - Obianyo, Obiamaka

AU - Causey, Corey P.

N1 - Download PDF Publication number US20100151506A1 US20100151506A1 US12/637,223 US63722309A US2010151506A1 US 20100151506 A1 US20100151506 A1 US 20100151506A1 US 63722309 A US63722309 A US 63722309A US 2010151506 A1 US2010151506 A1 US 2010151506A1Authority US United States Prior art keywords inhibitor amino acid acid peptide chloroacetamidine protein Prior art date Legal status (The legal status is an assumption and is not a legal conclusion.

PY - 2010

Y1 - 2010

N2 - U.S. Patent application, Serial No. 12 / 637,223. In accordance with certain embodiments of the present disclosure, a protein arginine methyltransferase inhibitor is provided. The inhibitor comprises an amino acid peptide joined to a chloroacetamidine warhead.

AB - U.S. Patent application, Serial No. 12 / 637,223. In accordance with certain embodiments of the present disclosure, a protein arginine methyltransferase inhibitor is provided. The inhibitor comprises an amino acid peptide joined to a chloroacetamidine warhead.

UR - https://patents.google.com/patent/US20100151506

M3 - Other

ER -

Chloroacetamidine Based Inhibitors and Activity Based Probes for the Protein Arginine Methytransferases

Abstract

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