Correlation of GAITRite Walkway System and Biodex Balance System Measures to the FARS Score in Friedreich's Ataxia Patients: A Validation Study

Theresa A. Zesiewicz; Seok Hun Kim; Clifton Gooch; Jennifer Farmer; Yangxin Huang; Jason Salemi; Israt Jahan; Kelly L. Sullivan; Lynn Weckers; Jeannie Stephenson

Correlation of GAITRite Walkway System and Biodex Balance System Measures to the FARS Score in Friedreich's Ataxia Patients: A Validation Study

Theresa A. Zesiewicz, Seok Hun Kim, Clifton Gooch, Jennifer Farmer, Yangxin Huang, Jason Salemi, Israt Jahan, Kelly L. Sullivan, Lynn Weckers, Jeannie Stephenson

Biostatistics, Epidemiology & Environmental Health Sciences

Research output: Contribution to conference › Presentation

Abstract

Objective: To test the validity of the GAITRite Walkway System and Biodex Balance System for measuring parameters of neurological dysfunction in Friedreich’s Ataxia (FA) patients against the standard of the Friedreich’s Ataxia Rating Scale (FARS). Background: FA is a neurodegenerative disease causing ataxia and cardiomyopathy. Precise measures are needed to test disease progression in FA in clinical trials. The GAITRite Walkway System and the Biodex Balance System are quantitative measures that evaluate gait and balance dysfunction using computerized technology. Design/Methods: In this prospective, longitudinal study, ambulatory FA patients were examined at baseline, and at 6, 12, and 24 months using the GAITRite and Biodex Systems and the FARS. Healthy, matched controls were tested at baseline and 12 months. All analyses were carried out using SAS 9.4. Results: Eight FA patients and 8 controls were included in this analysis. The following GAITRite parameters correlated significantly with the total FARS score in FA patients; comfortable walking velocity (r=-0.536; p Conclusions: In this study, multiple GAITRite and Biodex measures correlated significantly with the FARS scores, suggesting a high degree of clinical significance and providing evidence for validation of these measures in FA patients.

Original language	American English
State	Published - Apr 21 2015
Event	American Academy of Neurology Annual Meeting (AAN) - Duration: Apr 23 2018 → …

Conference

Conference	American Academy of Neurology Annual Meeting (AAN)
Period	04/23/18 → …

Disciplines

Epidemiology
Medicine and Health Sciences
Public Health

Keywords

Biodex Balance System
FARS Score
Friedreich’s Ataxia
GAITRite Walkway System
Patients

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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http://www.neurology.org/content/84/14_Supplement/P2.123.short?sid=a27919fc-cfae-4178-bebc-a755e0ae911c

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Zesiewicz, T. A., Kim, S. H., Gooch, C., Farmer, J., Huang, Y., Salemi, J., Jahan, I., Sullivan, K. L., Weckers, L., & Stephenson, J. (2015). Correlation of GAITRite Walkway System and Biodex Balance System Measures to the FARS Score in Friedreich's Ataxia Patients: A Validation Study. American Academy of Neurology Annual Meeting (AAN). http://www.neurology.org/content/84/14_Supplement/P2.123.short?sid=a27919fc-cfae-4178-bebc-a755e0ae911c

@conference{0865d835bf2848c58d1c8625ef694fd4,

title = "Correlation of GAITRite Walkway System and Biodex Balance System Measures to the FARS Score in Friedreich's Ataxia Patients: A Validation Study",

abstract = " Objective: To test the validity of the GAITRite Walkway System and Biodex Balance System for measuring parameters of neurological dysfunction in Friedreich’s Ataxia (FA) patients against the standard of the Friedreich’s Ataxia Rating Scale (FARS). Background: FA is a neurodegenerative disease causing ataxia and cardiomyopathy. Precise measures are needed to test disease progression in FA in clinical trials. The GAITRite Walkway System and the Biodex Balance System are quantitative measures that evaluate gait and balance dysfunction using computerized technology. Design/Methods: In this prospective, longitudinal study, ambulatory FA patients were examined at baseline, and at 6, 12, and 24 months using the GAITRite and Biodex Systems and the FARS. Healthy, matched controls were tested at baseline and 12 months. All analyses were carried out using SAS 9.4. Results: Eight FA patients and 8 controls were included in this analysis. The following GAITRite parameters correlated significantly with the total FARS score in FA patients; comfortable walking velocity (r=-0.536; p Conclusions: In this study, multiple GAITRite and Biodex measures correlated significantly with the FARS scores, suggesting a high degree of clinical significance and providing evidence for validation of these measures in FA patients. ",

keywords = "Biodex Balance System, FARS Score, Friedreich{\textquoteright}s Ataxia, GAITRite Walkway System, Patients",

author = "Zesiewicz, {Theresa A.} and Kim, {Seok Hun} and Clifton Gooch and Jennifer Farmer and Yangxin Huang and Jason Salemi and Israt Jahan and Sullivan, {Kelly L.} and Lynn Weckers and Jeannie Stephenson",

year = "2015",

month = apr,

day = "21",

language = "American English",

note = "American Academy of Neurology Annual Meeting (AAN) ; Conference date: 23-04-2018",

}

Zesiewicz, TA, Kim, SH, Gooch, C, Farmer, J, Huang, Y, Salemi, J, Jahan, I, Sullivan, KL, Weckers, L & Stephenson, J 2015, 'Correlation of GAITRite Walkway System and Biodex Balance System Measures to the FARS Score in Friedreich's Ataxia Patients: A Validation Study', American Academy of Neurology Annual Meeting (AAN), 04/23/18. <http://www.neurology.org/content/84/14_Supplement/P2.123.short?sid=a27919fc-cfae-4178-bebc-a755e0ae911c>

TY - CONF

T1 - Correlation of GAITRite Walkway System and Biodex Balance System Measures to the FARS Score in Friedreich's Ataxia Patients: A Validation Study

AU - Zesiewicz, Theresa A.

AU - Kim, Seok Hun

AU - Gooch, Clifton

AU - Farmer, Jennifer

AU - Huang, Yangxin

AU - Salemi, Jason

AU - Jahan, Israt

AU - Sullivan, Kelly L.

AU - Weckers, Lynn

AU - Stephenson, Jeannie

PY - 2015/4/21

Y1 - 2015/4/21

N2 - Objective: To test the validity of the GAITRite Walkway System and Biodex Balance System for measuring parameters of neurological dysfunction in Friedreich’s Ataxia (FA) patients against the standard of the Friedreich’s Ataxia Rating Scale (FARS). Background: FA is a neurodegenerative disease causing ataxia and cardiomyopathy. Precise measures are needed to test disease progression in FA in clinical trials. The GAITRite Walkway System and the Biodex Balance System are quantitative measures that evaluate gait and balance dysfunction using computerized technology. Design/Methods: In this prospective, longitudinal study, ambulatory FA patients were examined at baseline, and at 6, 12, and 24 months using the GAITRite and Biodex Systems and the FARS. Healthy, matched controls were tested at baseline and 12 months. All analyses were carried out using SAS 9.4. Results: Eight FA patients and 8 controls were included in this analysis. The following GAITRite parameters correlated significantly with the total FARS score in FA patients; comfortable walking velocity (r=-0.536; p Conclusions: In this study, multiple GAITRite and Biodex measures correlated significantly with the FARS scores, suggesting a high degree of clinical significance and providing evidence for validation of these measures in FA patients.

AB - Objective: To test the validity of the GAITRite Walkway System and Biodex Balance System for measuring parameters of neurological dysfunction in Friedreich’s Ataxia (FA) patients against the standard of the Friedreich’s Ataxia Rating Scale (FARS). Background: FA is a neurodegenerative disease causing ataxia and cardiomyopathy. Precise measures are needed to test disease progression in FA in clinical trials. The GAITRite Walkway System and the Biodex Balance System are quantitative measures that evaluate gait and balance dysfunction using computerized technology. Design/Methods: In this prospective, longitudinal study, ambulatory FA patients were examined at baseline, and at 6, 12, and 24 months using the GAITRite and Biodex Systems and the FARS. Healthy, matched controls were tested at baseline and 12 months. All analyses were carried out using SAS 9.4. Results: Eight FA patients and 8 controls were included in this analysis. The following GAITRite parameters correlated significantly with the total FARS score in FA patients; comfortable walking velocity (r=-0.536; p Conclusions: In this study, multiple GAITRite and Biodex measures correlated significantly with the FARS scores, suggesting a high degree of clinical significance and providing evidence for validation of these measures in FA patients.

KW - Biodex Balance System

KW - FARS Score

KW - Friedreich’s Ataxia

KW - GAITRite Walkway System

KW - Patients

UR - https://digitalcommons.georgiasouthern.edu/epid-facpres/3

UR - http://www.neurology.org/content/84/14_Supplement/P2.123.short?sid=a27919fc-cfae-4178-bebc-a755e0ae911c

M3 - Presentation

T2 - American Academy of Neurology Annual Meeting (AAN)

Y2 - 23 April 2018

ER -

Correlation of GAITRite Walkway System and Biodex Balance System Measures to the FARS Score in Friedreich's Ataxia Patients: A Validation Study

Abstract

Conference

Disciplines

Keywords

UN SDGs

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