Effect of Cortisol on Aquaporin Expression in the Oesophagus of the European Eel, Anguilla anguilla

Anne Sophie Martinez; Gillian Wilson; Claire Phillips; Christopher Cutler; Neil Hazon; Gordon Cramb

doi:10.1196/annals.1327.072

Effect of Cortisol on Aquaporin Expression in the Oesophagus of the European Eel, Anguilla anguilla

Anne Sophie Martinez, Gillian Wilson, Claire Phillips, Christopher Cutler, Neil Hazon, Gordon Cramb

Biology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory "silver" eels, but not in nonmigratory, immature "yellow" eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.

Original language	American English
Journal	Annals of the New York Academy of Sciences
Volume	1040
DOIs	https://doi.org/10.1196/annals.1327.072
State	Published - Apr 1 2005

Keywords

Anguilla anguilla
Aquaporin expression
Cortisol
Effect
Esophagus
European eel

DC Disciplines

Biology
Biochemistry, Biophysics, and Structural Biology

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https://doi.org/10.1196/annals.1327.072

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title = "Effect of Cortisol on Aquaporin Expression in the Oesophagus of the European Eel, Anguilla anguilla",

abstract = "Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory {"}silver{"} eels, but not in nonmigratory, immature {"}yellow{"} eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.",

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language = "American English",

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TY - JOUR

T1 - Effect of Cortisol on Aquaporin Expression in the Oesophagus of the European Eel, Anguilla anguilla

AU - Martinez, Anne Sophie

AU - Wilson, Gillian

AU - Phillips, Claire

AU - Cutler, Christopher

AU - Hazon, Neil

AU - Cramb, Gordon

PY - 2005/4/1

Y1 - 2005/4/1

N2 - Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory "silver" eels, but not in nonmigratory, immature "yellow" eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.

AB - Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory "silver" eels, but not in nonmigratory, immature "yellow" eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.

KW - Anguilla anguilla

KW - Aquaporin expression

KW - Cortisol

KW - Effect

KW - Esophagus

KW - European eel

UR - https://digitalcommons.georgiasouthern.edu/biology-facpubs/68

UR - https://doi.org/10.1196/annals.1327.072

U2 - 10.1196/annals.1327.072

DO - 10.1196/annals.1327.072

M3 - Article

SN - 0077-8923

VL - 1040

JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

ER -

Effect of Cortisol on Aquaporin Expression in the Oesophagus of the European Eel, Anguilla anguilla

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