Effect of cortisol on aquaporin expression in the esophagus of the European eel, Anguilla anguilla

Anne Sophie Martinez; Gillian Wilson; Claire Phillips; Christopher Cutler; Neil Hazon; Gordon Cramb

doi:10.1196/annals.1327.072

Effect of cortisol on aquaporin expression in the esophagus of the European eel, Anguilla anguilla

Anne Sophie Martinez
, Gillian Wilson
, Claire Phillips
, Christopher Cutler
, Neil Hazon
, Gordon Cramb

Biology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory "silver" eels, but not in nonmigratory, immature "yellow" eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.

Original language	English
Pages (from-to)	395-398
Number of pages	4
Journal	Annals of the New York Academy of Sciences
Volume	1040
DOIs	https://doi.org/10.1196/annals.1327.072
State	Published - 2005

Scopus Subject Areas

General Neuroscience
General Biochemistry, Genetics and Molecular Biology
History and Philosophy of Science

Keywords

Aquaporin
Cortisol
Esophagus
European eel
Seawater (SW) acclimation

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10.1196/annals.1327.072

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title = "Effect of cortisol on aquaporin expression in the esophagus of the European eel, Anguilla anguilla",

abstract = "Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory {"}silver{"} eels, but not in nonmigratory, immature {"}yellow{"} eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.",

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doi = "10.1196/annals.1327.072",

language = "English",

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pages = "395--398",

journal = "Annals of the New York Academy of Sciences",

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T1 - Effect of cortisol on aquaporin expression in the esophagus of the European eel, Anguilla anguilla

AU - Martinez, Anne Sophie

AU - Wilson, Gillian

AU - Phillips, Claire

AU - Cutler, Christopher

AU - Hazon, Neil

AU - Cramb, Gordon

PY - 2005

Y1 - 2005

N2 - Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory "silver" eels, but not in nonmigratory, immature "yellow" eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.

AB - Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory "silver" eels, but not in nonmigratory, immature "yellow" eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment.

KW - Aquaporin

KW - Cortisol

KW - Esophagus

KW - European eel

KW - Seawater (SW) acclimation

UR - https://www.scopus.com/pages/publications/22144465802

U2 - 10.1196/annals.1327.072

DO - 10.1196/annals.1327.072

M3 - Article

SN - 0077-8923

VL - 1040

SP - 395

EP - 398

JO - Annals of the New York Academy of Sciences

JF - Annals of the New York Academy of Sciences

ER -

Effect of cortisol on aquaporin expression in the esophagus of the European eel, Anguilla anguilla

Abstract

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