Abstract
This chapter elaborates on the role of epigenetic mechanisms in the expression of neurobehavioral outcomes in psychiatric disease, including mood and psychotic disorders, addiction, and aberrant responses to stress, fear, and anxiety. These disorders provide resourceful models to uncover pathways that network core central nervous system functions with emergent human behaviors. This chapter discusses how current epigenetic paradigms for noncoding RNAs, DNA methylation, and histone modifications significantly influence development and progression of symptoms in afflicted patients.
| Original language | English |
|---|---|
| Title of host publication | Epigenetics in Human Disease |
| Publisher | Elsevier |
| Pages | 251-267 |
| Number of pages | 17 |
| ISBN (Electronic) | 9780128122150 |
| ISBN (Print) | 9780128123294 |
| DOIs | |
| State | Published - Jan 1 2018 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Scopus Subject Areas
- General Medicine
- General Biochemistry, Genetics and Molecular Biology
Keywords
- Antisense RNA
- Circular RNA (circRNA)
- DNA methylation
- Epigenetics
- Long noncoding RNA (lncRNA)
- MicroRNA (miRNA)
- Neurobehavior
- Neurogenesis
- Noncoding RNAs
- Polymorphism
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