Evolving a Bayesian classifier for ECG-based age classification in medical applications

M. Wiggins, A. Saad, B. Litt, G. Vachtsevanos

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

Objective: To classify patients by age based upon information extracted from their electrocardiograms (ECGs). To develop and compare the performance of Bayesian classifiers. Methods and material: We present a methodology for classifying patients according to statistical features extracted from their ECG signals using a genetically evolved Bayesian network classifier. Continuous signal feature variables are converted to a discrete symbolic form by thresholding, to lower the dimensionality of the signal. This simplifies calculation of conditional probability tables for the classifier, and makes the tables smaller. Two methods of network discovery from data were developed and compared: the first using a greedy hill-climb search and the second employed evolutionary computing using a genetic algorithm (GA). Results and conclusions: The evolved Bayesian network performed better (86.25% AUC) than both the one developed using the greedy algorithm (65% AUC) and the naïve Bayesian classifier (84.75% AUC). The methodology for evolving the Bayesian classifier can be used to evolve Bayesian networks in general thereby identifying the dependencies among the variables of interest. Those dependencies are assumed to be non-existent by naïve Bayesian classifiers. Such a classifier can then be used for medical applications for diagnosis and prediction purposes.

Original languageEnglish
Pages (from-to)599-608
Number of pages10
JournalApplied Soft Computing
Volume8
Issue number1
DOIs
StatePublished - Jan 2008

Scopus Subject Areas

  • Software

Keywords

  • ECG-based age classification
  • Evolved Bayesian classifier
  • Hybrid soft computing techniques

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