Fentanyl-induced bradykinesia and rigidity after deep brain stimulation in a patient with parkinson disease

Theresa A. Zesiewicz; Robert A. Hauser; Alan Freeman; Kelly L. Sullivan; Amber M. Miller; Tariq Halim

doi:10.1097/WNF.0b013e31817e23e3

Fentanyl-induced bradykinesia and rigidity after deep brain stimulation in a patient with parkinson disease

Theresa A. Zesiewicz, Robert A. Hauser, Alan Freeman, Kelly L. Sullivan, Amber M. Miller, Tariq Halim

Biostatistics, Epidemiology & Environmental Health Sciences

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

A 58-year-old man with advanced Parkinson disease underwent battery replacement for a deep brain stimulator and experienced severe bradykinesia and rigidity postoperatively for 36 hours. The patient was administered fentanyl as an anesthetic during the procedure and as an analgesic periodically during the day after surgery. The severe bradykinesia and rigidity persisted despite reactivation of the deep brain stimulator and immediate reinstitution of Parkinson disease medications, but resolved completely several hours after discontinuation of fentanyl.

Original language	English
Pages (from-to)	48-50
Number of pages	3
Journal	Clinical Neuropharmacology
Volume	32
Issue number	1
DOIs	https://doi.org/10.1097/WNF.0b013e31817e23e3
State	Published - Jan 2009

Scopus Subject Areas

Pharmacology
Clinical Neurology
Pharmacology (medical)

Keywords

Deep brain stimulation
Fentanyl
Parkinson disease
Rigidity

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10.1097/WNF.0b013e31817e23e3License: Unspecified

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title = "Fentanyl-induced bradykinesia and rigidity after deep brain stimulation in a patient with parkinson disease",

abstract = "A 58-year-old man with advanced Parkinson disease underwent battery replacement for a deep brain stimulator and experienced severe bradykinesia and rigidity postoperatively for 36 hours. The patient was administered fentanyl as an anesthetic during the procedure and as an analgesic periodically during the day after surgery. The severe bradykinesia and rigidity persisted despite reactivation of the deep brain stimulator and immediate reinstitution of Parkinson disease medications, but resolved completely several hours after discontinuation of fentanyl.",

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AU - Hauser, Robert A.

AU - Freeman, Alan

AU - Sullivan, Kelly L.

AU - Miller, Amber M.

AU - Halim, Tariq

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N2 - A 58-year-old man with advanced Parkinson disease underwent battery replacement for a deep brain stimulator and experienced severe bradykinesia and rigidity postoperatively for 36 hours. The patient was administered fentanyl as an anesthetic during the procedure and as an analgesic periodically during the day after surgery. The severe bradykinesia and rigidity persisted despite reactivation of the deep brain stimulator and immediate reinstitution of Parkinson disease medications, but resolved completely several hours after discontinuation of fentanyl.

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KW - Fentanyl

KW - Parkinson disease

KW - Rigidity

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Fentanyl-induced bradykinesia and rigidity after deep brain stimulation in a patient with parkinson disease

Abstract

Scopus Subject Areas

Keywords

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