Genetically distinct hantaviruses in two bat species in Panamá

Karen Yamada; Fuka Kikuchi; Jonathan L. Dunnum; Pablo Gutiérrez-Moreno; Publio E. González D.; Blas Armién; Mihail Pérez-Callejas; Danielle Land; Jocelyn P. Colella; Tetsuya Mizutani; Ken Maeda; Motoi Suzuki; Stephen E. Greiman; Carlos Alberto Carrión-Bonilla; Joseph A. Cook; Richard Yanagihara; Satoru Arai

doi:10.1016/j.isci.2025.112749

Genetically distinct hantaviruses in two bat species in Panamá

Karen Yamada, Fuka Kikuchi, Jonathan L. Dunnum, Pablo Gutiérrez-Moreno, Publio E. González D., Blas Armién, Mihail Pérez-Callejas, Danielle Land, Jocelyn P. Colella, Tetsuya Mizutani, Ken Maeda, Motoi Suzuki, Stephen E. Greiman, Carlos Alberto Carrión-Bonilla, Joseph A. Cook, Richard Yanagihara, Satoru Arai

Biology

Research output: Contribution to journal › Article › peer-review

Abstract

Recent discoveries of hantaviruses in bats in Europe, Asia, and Africa have prompted expanded explorations of their host diversity and geographic distribution. In screening lung tissue of 218 bats from Panamá, representing 19 genera and five families, we detected hantavirus RNA in two of three greater sac-winged bats (Emballonuridae: Saccopteryx bilineata) and in four of 29 Seba's short-tailed bats (Phyllostomidae: Carollia perspicillata). Phylogenetic analyses of the small, medium, and large genomic segments revealed a newfound hantavirus in S. bilineata, tentatively designated Filo del Tallo virus, and the recently reported Buritiense virus in C. perspicillata. Both share common ancestry with bat-associated hantaviruses in Asia and Africa. These results indicate that bats serve as hosts of hantaviruses in the Americas. Given opportunities for close contact between humans and bats, studies on the genetic diversity, pathogenicity, and circulation dynamics of hantaviruses are urgently needed.

Original language	English
Article number	112749
Journal	iScience
Volume	28
Issue number	6
DOIs	https://doi.org/10.1016/j.isci.2025.112749
State	Published - May 26 2025

Scopus Subject Areas

General

Keywords

Microbiology
Virology
Zoology

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10.1016/j.isci.2025.112749

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Yamada, K., Kikuchi, F., Dunnum, J. L., Gutiérrez-Moreno, P., González D., P. E., Armién, B., Pérez-Callejas, M., Land, D., Colella, J. P., Mizutani, T., Maeda, K., Suzuki, M., Greiman, S. E., Carrión-Bonilla, C. A., Cook, J. A., Yanagihara, R., & Arai, S. (2025). Genetically distinct hantaviruses in two bat species in Panamá. iScience, 28(6), Article 112749. https://doi.org/10.1016/j.isci.2025.112749

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title = "Genetically distinct hantaviruses in two bat species in Panam{\'a}",

abstract = "Recent discoveries of hantaviruses in bats in Europe, Asia, and Africa have prompted expanded explorations of their host diversity and geographic distribution. In screening lung tissue of 218 bats from Panam{\'a}, representing 19 genera and five families, we detected hantavirus RNA in two of three greater sac-winged bats (Emballonuridae: Saccopteryx bilineata) and in four of 29 Seba's short-tailed bats (Phyllostomidae: Carollia perspicillata). Phylogenetic analyses of the small, medium, and large genomic segments revealed a newfound hantavirus in S. bilineata, tentatively designated Filo del Tallo virus, and the recently reported Buritiense virus in C. perspicillata. Both share common ancestry with bat-associated hantaviruses in Asia and Africa. These results indicate that bats serve as hosts of hantaviruses in the Americas. Given opportunities for close contact between humans and bats, studies on the genetic diversity, pathogenicity, and circulation dynamics of hantaviruses are urgently needed.",

keywords = "Microbiology, Virology, Zoology",

author = "Karen Yamada and Fuka Kikuchi and Dunnum, \{Jonathan L.\} and Pablo Guti{\'e}rrez-Moreno and \{Gonz{\'a}lez D.\}, \{Publio E.\} and Blas Armi{\'e}n and Mihail P{\'e}rez-Callejas and Danielle Land and Colella, \{Jocelyn P.\} and Tetsuya Mizutani and Ken Maeda and Motoi Suzuki and Greiman, \{Stephen E.\} and Carri{\'o}n-Bonilla, \{Carlos Alberto\} and Cook, \{Joseph A.\} and Richard Yanagihara and Satoru Arai",

note = "{\textcopyright} 2025 The Author(s).",

year = "2025",

month = may,

day = "26",

doi = "10.1016/j.isci.2025.112749",

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Yamada, K, Kikuchi, F, Dunnum, JL, Gutiérrez-Moreno, P, González D., PE, Armién, B, Pérez-Callejas, M, Land, D, Colella, JP, Mizutani, T, Maeda, K, Suzuki, M, Greiman, SE, Carrión-Bonilla, CA, Cook, JA, Yanagihara, R & Arai, S 2025, 'Genetically distinct hantaviruses in two bat species in Panamá', iScience, vol. 28, no. 6, 112749. https://doi.org/10.1016/j.isci.2025.112749

TY - JOUR

T1 - Genetically distinct hantaviruses in two bat species in Panamá

AU - Yamada, Karen

AU - Kikuchi, Fuka

AU - Dunnum, Jonathan L.

AU - Gutiérrez-Moreno, Pablo

AU - González D., Publio E.

AU - Armién, Blas

AU - Pérez-Callejas, Mihail

AU - Land, Danielle

AU - Colella, Jocelyn P.

AU - Mizutani, Tetsuya

AU - Maeda, Ken

AU - Suzuki, Motoi

AU - Greiman, Stephen E.

AU - Carrión-Bonilla, Carlos Alberto

AU - Cook, Joseph A.

AU - Yanagihara, Richard

AU - Arai, Satoru

PY - 2025/5/26

Y1 - 2025/5/26

N2 - Recent discoveries of hantaviruses in bats in Europe, Asia, and Africa have prompted expanded explorations of their host diversity and geographic distribution. In screening lung tissue of 218 bats from Panamá, representing 19 genera and five families, we detected hantavirus RNA in two of three greater sac-winged bats (Emballonuridae: Saccopteryx bilineata) and in four of 29 Seba's short-tailed bats (Phyllostomidae: Carollia perspicillata). Phylogenetic analyses of the small, medium, and large genomic segments revealed a newfound hantavirus in S. bilineata, tentatively designated Filo del Tallo virus, and the recently reported Buritiense virus in C. perspicillata. Both share common ancestry with bat-associated hantaviruses in Asia and Africa. These results indicate that bats serve as hosts of hantaviruses in the Americas. Given opportunities for close contact between humans and bats, studies on the genetic diversity, pathogenicity, and circulation dynamics of hantaviruses are urgently needed.

AB - Recent discoveries of hantaviruses in bats in Europe, Asia, and Africa have prompted expanded explorations of their host diversity and geographic distribution. In screening lung tissue of 218 bats from Panamá, representing 19 genera and five families, we detected hantavirus RNA in two of three greater sac-winged bats (Emballonuridae: Saccopteryx bilineata) and in four of 29 Seba's short-tailed bats (Phyllostomidae: Carollia perspicillata). Phylogenetic analyses of the small, medium, and large genomic segments revealed a newfound hantavirus in S. bilineata, tentatively designated Filo del Tallo virus, and the recently reported Buritiense virus in C. perspicillata. Both share common ancestry with bat-associated hantaviruses in Asia and Africa. These results indicate that bats serve as hosts of hantaviruses in the Americas. Given opportunities for close contact between humans and bats, studies on the genetic diversity, pathogenicity, and circulation dynamics of hantaviruses are urgently needed.

KW - Microbiology

KW - Virology

KW - Zoology

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U2 - 10.1016/j.isci.2025.112749

DO - 10.1016/j.isci.2025.112749

M3 - Article

C2 - 40546951

AN - SCOPUS:105007435532

SN - 2589-0042

VL - 28

JO - iScience

JF - iScience

IS - 6

M1 - 112749

ER -

Genetically distinct hantaviruses in two bat species in Panamá

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