High-efficiency immunoassay platforms with controllable surface roughness and oriented antibody immobilization

Lingjie Song; Jie Zhao; Shifang Luan; Jiao Ma; Weihua Ming; Jinghua Yin

doi:10.1039/c5tb01164g

High-efficiency immunoassay platforms with controllable surface roughness and oriented antibody immobilization

Lingjie Song, Jie Zhao, Shifang Luan, Jiao Ma, Weihua Ming, Jinghua Yin

Biochemistry, Chemistry, & Physics

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

High-efficiency immunoassay platforms with controlled surface roughness (single- and dual-scale structured surface) were prepared by combining a facile layer-by-layer particle deposition approach with oriented immobilization of antibodies through boronic acid moieties. The as-prepared surfaces showed significantly enhanced antibody loading capacity and antigen recognition, as proved by fluorescence images.

Original language	English
Pages (from-to)	7499-7502
Number of pages	4
Journal	Journal of Materials Chemistry B
Volume	3
Issue number	38
DOIs	https://doi.org/10.1039/c5tb01164g
State	Published - Sep 7 2015

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title = "High-efficiency immunoassay platforms with controllable surface roughness and oriented antibody immobilization",

abstract = "High-efficiency immunoassay platforms with controlled surface roughness (single- and dual-scale structured surface) were prepared by combining a facile layer-by-layer particle deposition approach with oriented immobilization of antibodies through boronic acid moieties. The as-prepared surfaces showed significantly enhanced antibody loading capacity and antigen recognition, as proved by fluorescence images.",

author = "Lingjie Song and Jie Zhao and Shifang Luan and Jiao Ma and Weihua Ming and Jinghua Yin",

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T1 - High-efficiency immunoassay platforms with controllable surface roughness and oriented antibody immobilization

AU - Song, Lingjie

AU - Zhao, Jie

AU - Luan, Shifang

AU - Ma, Jiao

AU - Ming, Weihua

AU - Yin, Jinghua

PY - 2015/9/7

Y1 - 2015/9/7

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AB - High-efficiency immunoassay platforms with controlled surface roughness (single- and dual-scale structured surface) were prepared by combining a facile layer-by-layer particle deposition approach with oriented immobilization of antibodies through boronic acid moieties. The as-prepared surfaces showed significantly enhanced antibody loading capacity and antigen recognition, as proved by fluorescence images.

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U2 - 10.1039/c5tb01164g

DO - 10.1039/c5tb01164g

M3 - Article

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SP - 7499

EP - 7502

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 38

ER -

High-efficiency immunoassay platforms with controllable surface roughness and oriented antibody immobilization

Abstract

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