Issledovanie protektivnoǐ aktivnosti individual'nykh belkov i immunogennykh fraktsiǐ, vydelennykh iz Rickettsia prowazekii.

M. E. Eremeeva; N. M. Balaeva; V. A. Genig; A. V. Rodionov; L. S. Belousova; I. P. Isachkova

Issledovanie protektivnoǐ aktivnosti individual'nykh belkov i immunogennykh fraktsiǐ, vydelennykh iz Rickettsia prowazekii.

Translated title of the contribution: The protective activity of individual proteins and immunogenic fractions isolated from Rickettsia prowazekii

M. E. Eremeeva
, N. M. Balaeva
, V. A. Genig
, A. V. Rodionov
, L. S. Belousova
, I. P. Isachkova

Biostatistics, Epidemiology & Environmental Health Sciences

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The immunogenic properties and protective activity of basic protein I and tris-soluble antigens isolated from R. prowazekii were analyzed in comparison with those of chemical typhus vaccine on the model of anti-infectious immunity in guinea pigs. The analysis revealed that purified protein I has protective activity for guinea pigs, which is less pronounced in protein I from strain E with weak pathogenicity than protein I from strains EVir and Breinl. The activity and immunogenic properties of tris-soluble antigens, especially antigen I, are comparable with those of chemical typhus vaccines in the parameters under study.

Translated title of the contribution	The protective activity of individual proteins and immunogenic fractions isolated from Rickettsia prowazekii
Original language	Russian
Pages (from-to)	95-100
Number of pages	6
Journal	Zhurnal Mikrobiologii Epidemiologii i Immunobiologii
Issue number	1
State	Published - Jan 1994

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Scopus Subject Areas

General Medicine

Cite this

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title = "Issledovanie protektivnoǐ aktivnosti individual'nykh belkov i immunogennykh fraktsiǐ, vydelennykh iz Rickettsia prowazekii.",

abstract = "The immunogenic properties and protective activity of basic protein I and tris-soluble antigens isolated from R. prowazekii were analyzed in comparison with those of chemical typhus vaccine on the model of anti-infectious immunity in guinea pigs. The analysis revealed that purified protein I has protective activity for guinea pigs, which is less pronounced in protein I from strain E with weak pathogenicity than protein I from strains EVir and Breinl. The activity and immunogenic properties of tris-soluble antigens, especially antigen I, are comparable with those of chemical typhus vaccines in the parameters under study.",

author = "Eremeeva, \{M. E.\} and Balaeva, \{N. M.\} and Genig, \{V. A.\} and Rodionov, \{A. V.\} and Belousova, \{L. S.\} and Isachkova, \{I. P.\}",

year = "1994",

month = jan,

language = "Russian",

pages = "95--100",

journal = "Zhurnal Mikrobiologii Epidemiologii i Immunobiologii",

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T1 - Issledovanie protektivnoǐ aktivnosti individual'nykh belkov i immunogennykh fraktsiǐ, vydelennykh iz Rickettsia prowazekii.

AU - Eremeeva, M. E.

AU - Balaeva, N. M.

AU - Genig, V. A.

AU - Rodionov, A. V.

AU - Belousova, L. S.

AU - Isachkova, I. P.

PY - 1994/1

Y1 - 1994/1

N2 - The immunogenic properties and protective activity of basic protein I and tris-soluble antigens isolated from R. prowazekii were analyzed in comparison with those of chemical typhus vaccine on the model of anti-infectious immunity in guinea pigs. The analysis revealed that purified protein I has protective activity for guinea pigs, which is less pronounced in protein I from strain E with weak pathogenicity than protein I from strains EVir and Breinl. The activity and immunogenic properties of tris-soluble antigens, especially antigen I, are comparable with those of chemical typhus vaccines in the parameters under study.

AB - The immunogenic properties and protective activity of basic protein I and tris-soluble antigens isolated from R. prowazekii were analyzed in comparison with those of chemical typhus vaccine on the model of anti-infectious immunity in guinea pigs. The analysis revealed that purified protein I has protective activity for guinea pigs, which is less pronounced in protein I from strain E with weak pathogenicity than protein I from strains EVir and Breinl. The activity and immunogenic properties of tris-soluble antigens, especially antigen I, are comparable with those of chemical typhus vaccines in the parameters under study.

UR - https://www.scopus.com/pages/publications/0028248797

M3 - Article

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AN - SCOPUS:0028248797

SN - 0372-9311

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JO - Zhurnal Mikrobiologii Epidemiologii i Immunobiologii

JF - Zhurnal Mikrobiologii Epidemiologii i Immunobiologii

IS - 1

ER -

Issledovanie protektivnoǐ aktivnosti individual'nykh belkov i immunogennykh fraktsiǐ, vydelennykh iz Rickettsia prowazekii.

Abstract

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