Levetiracetam-Induced Parkinsonism in a Huntington’s Disease Patient

Kelly L. Sullivan; Theresa A. Zesiewicz; Juan Sanchez-Ramos; Robert A. Hauser

doi:10.1097/01.wnf.0000169732.00690.32

Levetiracetam-Induced Parkinsonism in a Huntington’s Disease Patient

Kelly L. Sullivan, Theresa A. Zesiewicz, Juan Sanchez-Ramos, Robert A. Hauser

Biostatistics, Epidemiology & Environmental Health Sciences

University of South Florida

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The authors present a man with Huntington disease who was treated with levetiracetam (Keppra) in an effort to reduce chorea. Chorea was markedly reduced, but the patient developed parkinsonism and lethargy after 6 weeks of treatment. Symptoms consisted of resting tremor, rigidity, increased dystonia, and gait difficulty. Side effects from levetiracetam resolved completely within 7 days of levetiracetam discontinuation, and chorea returned to baseline.

Original language	American English
Journal	Clinical Neuropharmacol
Volume	28
DOIs	https://doi.org/10.1097/01.wnf.0000169732.00690.32
State	Published - Jul 28 2005

Disciplines

Public Health

Keywords

Huntington Disease
Levetiracetam-Induced Parkinsonism
Patient

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10.1097/01.wnf.0000169732.00690.32License: Unspecified

Cite this

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title = "Levetiracetam-Induced Parkinsonism in a Huntington{\textquoteright}s Disease Patient",

abstract = " The authors present a man with Huntington disease who was treated with levetiracetam (Keppra) in an effort to reduce chorea. Chorea was markedly reduced, but the patient developed parkinsonism and lethargy after 6 weeks of treatment. Symptoms consisted of resting tremor, rigidity, increased dystonia, and gait difficulty. Side effects from levetiracetam resolved completely within 7 days of levetiracetam discontinuation, and chorea returned to baseline.",

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AU - Zesiewicz, Theresa A.

AU - Sanchez-Ramos, Juan

AU - Hauser, Robert A.

PY - 2005/7/28

Y1 - 2005/7/28

N2 - The authors present a man with Huntington disease who was treated with levetiracetam (Keppra) in an effort to reduce chorea. Chorea was markedly reduced, but the patient developed parkinsonism and lethargy after 6 weeks of treatment. Symptoms consisted of resting tremor, rigidity, increased dystonia, and gait difficulty. Side effects from levetiracetam resolved completely within 7 days of levetiracetam discontinuation, and chorea returned to baseline.

AB - The authors present a man with Huntington disease who was treated with levetiracetam (Keppra) in an effort to reduce chorea. Chorea was markedly reduced, but the patient developed parkinsonism and lethargy after 6 weeks of treatment. Symptoms consisted of resting tremor, rigidity, increased dystonia, and gait difficulty. Side effects from levetiracetam resolved completely within 7 days of levetiracetam discontinuation, and chorea returned to baseline.

KW - Huntington Disease

KW - Levetiracetam-Induced Parkinsonism

KW - Patient

UR - https://doi.org/10.1097/01.wnf.0000169732.00690.32

U2 - 10.1097/01.wnf.0000169732.00690.32

DO - 10.1097/01.wnf.0000169732.00690.32

M3 - Article

VL - 28

JO - Clinical Neuropharmacol

JF - Clinical Neuropharmacol

ER -

Levetiracetam-Induced Parkinsonism in a Huntington’s Disease Patient

Abstract

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Keywords

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