Microwave-Assisted Preparation of Trifluoroacetaldehyde (Fluoral): Isolation and its Application

Shainaz M. Landge, Dmitry A. Borkin, Béla Török

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25 Scopus citations

Abstract

A novel method for the preparation of trifluoroacetaldehyde (fluoral, TFAc, CF3CHO) from commercially available trifluoroacetaldehyde ethylhemiacetal (TFAE) by microwave irradiation is described. The isolation, characterization and reaction of fluoral with various nucleophiles were studied to verify the diverse applicability of this new method.
Original languageAmerican English
JournalTetrahedron Letters
Volume48
DOIs
StatePublished - Sep 3 2007

Keywords

  • Fluoral
  • Microwave irradiation
  • Trifluoroacetaldehyde
  • Trifluoromethylated alcohols

DC Disciplines

  • Chemistry

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