Abstract
Misclassification of binary covariates often occurs in survival data and any survival data analysis ignoring such misclassification will result in estimation bias. To handle such misclassification, the misclassification simulation extrapolation (MC-SIMEX) procedure is a flexible method proposed in survival data analysis, which has been investigated extensively for right-censored survival data. However, the performance of the MC-SIMEX method has not been explored enough for interval-censored survival data. This chapter is aimed to investigate the performance of the MC-SIMEX procedure to interval-censored survival data through Monte-Carlo simulations and real data analysis. This investigation focuses on the log-logistic accelerated failure time (AFT) model since the log-logistic distribution plays an important role in evaluating non-monotonic hazards for survival data.
Original language | American English |
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Title of host publication | Emerging Topics in Modeling Interval-Censored Survival Data |
DOIs | |
State | Published - Nov 30 2022 |
Keywords
- Measurement error
- Misclassification
- SIMEX
- Survival analysis
DC Disciplines
- Biostatistics
- Epidemiology