Molecular Epidemiology of Rickettsial Diseases

Research output: Contribution to book or proceedingChapter

2 Scopus citations

Abstract

This chapter summarizes the classical methods used to investigate rickettsioses initially discovered and characterized in the United States with an emphasis on their role in understanding their epidemiology. More recent molecular methodologies used to diagnose and characterize rickettsioses and rickettsial agents are then presented. New epidemiological insights into rickettsioses that have been obtained by using these molecular tools are then reviewed. Finally, the limitations of contemporary tools used in the molecular epidemiology of rickettsioses are examined and discussed in the context of new opportunities for improvement of these current approaches.

Original languageAmerican English
Title of host publicationRickettsiales: Biology, Epidemiology, Molecular Biology and Vaccine Development
DOIs
StatePublished - Jan 1 2016

Disciplines

  • Environmental Health
  • Public Health
  • Environmental Public Health
  • Environmental Health and Protection

Keywords

  • Biomarkers
  • Molecular epidemiology
  • Pathogen discovery
  • Rickettsiae
  • Rickettsial diseases
  • Surveillance
  • Vaccine development

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