TY - JOUR
T1 - Molecular Physiology of Osmoregulation in Eels and Other Teleosts
T2 - The Role of Transporter Isoforms and Gene Duplication
AU - Cutler, Christopher P.
AU - Cramb, Gordon
PY - 2001/10
Y1 - 2001/10
N2 - This review focuses on recent developments in the molecular biology of ion and water transporter genes in fish and the potential role of their products in osmoregulation in both freshwater and seawater environments. In particular details of isoforms of various ATPases, co-transporters, exchangers and ion channels in the eel as well as other teleost species are described. Many of the teleost transporter isoforms discovered so far, appear to occur as twin or duplicate copies compared to their homologous counterparts in higher vertebrates, although these duplicate isoforms often have distinct tissue-specific and developmental stage-dependent expression patterns. The possible meaning of this information will be examined in relation to the fish genome duplication debate.
AB - This review focuses on recent developments in the molecular biology of ion and water transporter genes in fish and the potential role of their products in osmoregulation in both freshwater and seawater environments. In particular details of isoforms of various ATPases, co-transporters, exchangers and ion channels in the eel as well as other teleost species are described. Many of the teleost transporter isoforms discovered so far, appear to occur as twin or duplicate copies compared to their homologous counterparts in higher vertebrates, although these duplicate isoforms often have distinct tissue-specific and developmental stage-dependent expression patterns. The possible meaning of this information will be examined in relation to the fish genome duplication debate.
KW - Eels
KW - Gene duplication
KW - Molecular physiology
KW - Osmoregulation
KW - Teleosts
KW - Transporter isoforms
UR - https://doi.org/10.1016/S1095-6433(01)00435-4
U2 - 10.1016/S1095-6433(01)00435-4
DO - 10.1016/S1095-6433(01)00435-4
M3 - Article
VL - 130
JO - Comparative Biochemistry and Physiology, Part A: Molecular & Integrative Physiology
JF - Comparative Biochemistry and Physiology, Part A: Molecular & Integrative Physiology
ER -