On a Novel SVEIRS Markov chain epidemic model with multiple discrete delays and infection rates: modeling and sensitivity analysis to determine vaccination effects

Divine Wanduku, Omotomilola Jegede, Chinmoy Rahul, Broderick Oluyede, Oluwaseun Farotimi

Research output: Contribution to book or proceedingChapterpeer-review

2 Scopus citations

Abstract

A novel discrete time general Markov chain SVEIRS (Susceptible-Vaccinated-Exposed-Infected-Recovered-Susceptible) epidemic model is derived and studied. The model incorporates finite delay times for disease incubation, natural immunity, artificial immunity, and the period of infectiousness of infected individuals. The novel platform for representing different states of the disease in the population utilizes two discrete time measures for the current time of a person's state and also how long a person has been in the current state. Two submodels are derived based on whether the drive to get vaccinated is inspired by close contacts with infectious individuals or otherwise. Sensitivity analysis is conducted on the two submodels to determine how vaccination affects disease eradication.

Original languageEnglish
Title of host publicationAdvances in Epidemiological Modeling and Control of Viruses
PublisherElsevier
Pages95-143
Number of pages49
ISBN (Electronic)9780323995573
ISBN (Print)9780323995580
DOIs
StatePublished - Jan 1 2023

Scopus Subject Areas

  • General Economics, Econometrics and Finance
  • General Business, Management and Accounting

Keywords

  • Chain-binomial models
  • Correlated vaccination-infection rates
  • Discrete time delays
  • Markov chains
  • SVEIRS epidemic model
  • Vaccination impacts

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