Abstract
Whether a one-sided or a two-sided ρ value should be used for reporting the results of an analysis should be determined by the a priori question the investigation seeks to answer. It is concluded that one-sided ρ values are appropriate in clinical trials whose objective is to provide definitive, confirmatory evidence of efficacy of pharmaceutical compounds.
| Original language | American English |
|---|---|
| Journal | Journal of Biopharmaceutical Statistics |
| Volume | 1 |
| DOIs | |
| State | Published - 1991 |
Disciplines
- Public Health
- Biostatistics
Keywords
- Hypothesis tests
- One-sided
- Trial objective
- Two-sided
- ρ values
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