Rickettsia africae sp. nov., the etiological agent of African tick bite fever

Patrick J. Kelly, Lorenza Beati, Peter R. Mason, Linda A. Matthewman, Véronique Roux, Didier Raoult

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154 Scopus citations

Abstract

We propose the name Rickettsia africae sp. nov. (with type strain Z9-Hu) for a distinct species of spotted fever group (SFG) rickettsiae that is the etiological agent of African tick bite fever in humans. This rickettsia has a distinct natural cycle and can he phenotypically distinguished from the other SFG riekettsiae by microimmunofluorescence serotyping, by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and by Western blotting (immunoblotting). Genotypic differences between R. africae and the other SFG riekettsiae can be demonstrated by PCR restriction fragment length polymorphism analysis, pulsed-field gel electrophoresis, and sequencing of the 16S rRNA gene.

Original languageEnglish
Pages (from-to)611-614
Number of pages4
JournalInternational Journal of Systematic Bacteriology
Volume46
Issue number2
DOIs
StatePublished - Apr 1996
Externally publishedYes

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