Rickettsia africae sp. nov., the etiological agent of African tick bite fever

  • Patrick J. Kelly
  • , Lorenza Beati
  • , Peter R. Mason
  • , Linda A. Matthewman
  • , Véronique Roux
  • , Didier Raoult

Research output: Contribution to journalArticlepeer-review

161 Scopus citations

Abstract

We propose the name Rickettsia africae sp. nov. (with type strain Z9-Hu) for a distinct species of spotted fever group (SFG) rickettsiae that is the etiological agent of African tick bite fever in humans. This rickettsia has a distinct natural cycle and can he phenotypically distinguished from the other SFG riekettsiae by microimmunofluorescence serotyping, by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and by Western blotting (immunoblotting). Genotypic differences between R. africae and the other SFG riekettsiae can be demonstrated by PCR restriction fragment length polymorphism analysis, pulsed-field gel electrophoresis, and sequencing of the 16S rRNA gene.

Original languageEnglish
Pages (from-to)611-614
Number of pages4
JournalInternational Journal of Systematic Bacteriology
Volume46
Issue number2
DOIs
StatePublished - Apr 1996
Externally publishedYes

Scopus Subject Areas

  • Microbiology
  • Immunology

Fingerprint

Dive into the research topics of 'Rickettsia africae sp. nov., the etiological agent of African tick bite fever'. Together they form a unique fingerprint.

Cite this