TY - JOUR
T1 - SARS-CoV-2 Transmission in Alberta, British Columbia, and Ontario, Canada, January 2020-January 2022
AU - Kehoe, Aubrey D.
AU - Mallhi, Arshpreet Kaur
AU - Barton, Charles R.
AU - Martin, Hunter M.
AU - Turner, Christopher M.
AU - Hua, Xinyi
AU - Kwok, Kin On
AU - Chowell, Gerardo
AU - Fung, Isaac Chun Hai
N1 - Publisher Copyright:
© 2024 Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2024/5
Y1 - 2024/5
N2 - We estimated COVID-19 transmission potential and case burden by variant type in Alberta, British Columbia, and Ontario, Canada, during January 23, 2020-January 27, 2022; we also estimated the effectiveness of public health interventions to reduce transmission. We estimated time-varying reproduction number (Rt) over 7-day sliding windows and nonoverlapping time-windows determined by timing of policy changes. We calculated incidence rate ratios (IRRs) for each variant and compared rates to determine differences in burden among provinces. Rt corresponding with emergence of the Delta variant increased in all 3 provinces; British Columbia had the largest increase, 43.85% (95% credible interval [CrI] 40.71%-46.84%). Across the study period, IRR was highest for Omicron (8.74 [95% CrI 8.71-8.77]) and burden highest in Alberta (IRR 1.80 [95% CrI 1.79-1.81]). Initiating public health interventions was associated with lower Rt and relaxing restrictions and emergence of new variants associated with increases in Rt
AB - We estimated COVID-19 transmission potential and case burden by variant type in Alberta, British Columbia, and Ontario, Canada, during January 23, 2020-January 27, 2022; we also estimated the effectiveness of public health interventions to reduce transmission. We estimated time-varying reproduction number (Rt) over 7-day sliding windows and nonoverlapping time-windows determined by timing of policy changes. We calculated incidence rate ratios (IRRs) for each variant and compared rates to determine differences in burden among provinces. Rt corresponding with emergence of the Delta variant increased in all 3 provinces; British Columbia had the largest increase, 43.85% (95% credible interval [CrI] 40.71%-46.84%). Across the study period, IRR was highest for Omicron (8.74 [95% CrI 8.71-8.77]) and burden highest in Alberta (IRR 1.80 [95% CrI 1.79-1.81]). Initiating public health interventions was associated with lower Rt and relaxing restrictions and emergence of new variants associated with increases in Rt
KW - Alberta/epidemiology
KW - Basic Reproduction Number
KW - British Columbia/epidemiology
KW - COVID-19/epidemiology
KW - Humans
KW - Incidence
KW - Ontario/epidemiology
KW - Public Health
KW - SARS-CoV-2
UR - https://www.scopus.com/pages/publications/85191433216
U2 - 10.3201/eid3005.230482
DO - 10.3201/eid3005.230482
M3 - Article
C2 - 38666622
AN - SCOPUS:85191433216
SN - 1080-6040
VL - 30
SP - 956
EP - 967
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 5
ER -
