Semiconducting Silicon Nanowire Array Fabrication for High Throughput Screening in the Biosciences

This chapter discusses various strategies to fabricate silicon nanowire field effect transistor arrays for high throughput screening in the biosciences. At the beginning, three major strategies to fabricate addressable nanowire field effect transistor arrays are reviewed, as well as their interfacing to microfluidic devices and other complementary characterization instruments for high throughput screening. Then the underlying mechanisms of screening and practical applications in the field of DNA hybridization, virus detection, cancer diagnosis and recording of cell signals are discussed. Finally, future research trends and important reference resources are given.