Successful Knockdown of Aquaporin 1 (AQP1) Protein Expression in American Eel (Anguilla rostrata) Gastrointestinal Tract Using Direct-Infusions of Vivo-Morpholinos

Christopher P. Cutler, Paige Tanner

Research output: Contribution to journalArticlepeer-review

Abstract

Vivo-morpholinos are artificial nucleic acids that can block the protein production from a particular gene. Direct intestinal infusions of vivo-morpholinos were used to ‘knockdown’ (reduce) the amount of aquaporin 1 water channel protein to be able to see differences in function with or without the protein.

Original languageAmerican English
JournalThe Bulletin: Mount Desert Island Biological Laboratory
Volume53
StatePublished - Jan 1 2014

Disciplines

  • Biochemistry, Biophysics, and Structural Biology
  • Biology

Keywords

  • AQP1
  • American eel
  • Anguilla rostrata
  • Aquaporin 1
  • Direct-infusions
  • Gastrointestinal tract
  • Knockdown
  • Protein expression
  • Vivo-morpholinos

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