@article{26b7c4b51eb9428682afaa68387f7b0d,
title = "Synthesis of Pyrazoles by a One-Pot Tandem Cyclization-Dehydrogenation Approach on Pd/C/K-10 Catalyst",
abstract = " A novel one-pot synthesis of substituted pyrazoles from chalcones and hydrazines via a tandem cyclization-dehydrogenation approach is described. This process is based on the use of a bifunctional noble-metal/solid-acid catalyst, Pd/C/K-10 montmorillonite and microwave irradiation under solvent-free conditions. The cyclization of chalcones with hydrazines readily takes place on the strong solid acid while the presence of the metal ensures the formation of the aromatic product through dehydrogenation. The reactions are complete in 30 minutes providing good yields and high selectivities. ",
keywords = "Bifunctional catalysis, Chalcones, Hydrazines, Microwave heating, Pyrazoles",
author = "Landge, {Shainaz M.} and Allison Schmidt and Outerbridge, {Verona M.} and B{\'e}la T{\"o}r{\"o}k",
note = "Synlett 2007(10): 1600-1604 DOI: 10.1055/s-2007-982545 {\textcopyright} Georg Thieme Verlag Stuttgart · New York Shainaz M. Landge, Allison Schmidt, Verona Outerbridge, B{\'e}la T{\"o}r{\"o}k*Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd., Boston, MA 02125, USAFax: +1(617)2876030; e-Mail:
[email protected]; Further Information A novel one-pot synthesis of substituted pyrazoles from chalcones and hydrazines via a tandem cyclization-dehydrogenation approach is described.",
year = "2007",
month = mar,
doi = "10.1055/s-2007-982545",
language = "American English",
volume = "10",
journal = "Synlett",
issn = "0936-5214",
publisher = "Georg Thieme Verlag",
}