Tegaserod (Zelnorm) for the Treatment of Constipation in Parkinson’s Disease

Kelly L. Sullivan; Joseph S. Staffetti; Robert A. Hauser; Peter B. Dunne; Theresa A. Zesiewicz

doi:10.1002/mds.20666

Tegaserod (Zelnorm) for the Treatment of Constipation in Parkinson’s Disease

Kelly L. Sullivan, Joseph S. Staffetti, Robert A. Hauser, Peter B. Dunne, Theresa A. Zesiewicz

Biostatistics, Epidemiology & Environmental Health Sciences

University of South Florida

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

<div class="line" id="line-5"> We performed a double&hyphen;blind randomized placebo&hyphen;controlled pilot study to determine the efficacy of tegaserod (Zelnorm) in treating constipation in 15 patients with Parkinson's disease (PD). There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS).</div>

Original language	American English
Journal	Movement Disorders
Volume	21
DOIs	https://doi.org/10.1002/mds.20666
State	Published - Jan 21 2006

Disciplines

Public Health

Keywords

Parkinson's Disease
Tegaerod
Zelnorm

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abstract = " We performed a double&hyphen;blind randomized placebo&hyphen;controlled pilot study to determine the efficacy of tegaserod (Zelnorm) in treating constipation in 15 patients with Parkinson's disease (PD). There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS).",

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AU - Staffetti, Joseph S.

AU - Hauser, Robert A.

AU - Dunne, Peter B.

AU - Zesiewicz, Theresa A.

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N2 - We performed a double&hyphen;blind randomized placebo&hyphen;controlled pilot study to determine the efficacy of tegaserod (Zelnorm) in treating constipation in 15 patients with Parkinson's disease (PD). There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS).

AB - We performed a double&hyphen;blind randomized placebo&hyphen;controlled pilot study to determine the efficacy of tegaserod (Zelnorm) in treating constipation in 15 patients with Parkinson's disease (PD). There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS).

KW - Parkinson's Disease

KW - Tegaerod

KW - Zelnorm

UR - https://doi.org/10.1002/mds.20666

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DO - 10.1002/mds.20666

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VL - 21

JO - Movement Disorders

JF - Movement Disorders

ER -

Tegaserod (Zelnorm) for the Treatment of Constipation in Parkinson’s Disease

Abstract

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Keywords

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