Tegaserod (Zelnorm) for the treatment of constipation in Parkinson's disease

Kelly L. Sullivan; Joseph S. Staffetti; Robert A. Hauser; Peter B. Dunne; Theresa A. Zesiewicz

doi:10.1002/mds.20666

Tegaserod (Zelnorm) for the treatment of constipation in Parkinson's disease

Kelly L. Sullivan
, Joseph S. Staffetti
, Robert A. Hauser
, Peter B. Dunne
, Theresa A. Zesiewicz

Biostatistics, Epidemiology & Environmental Health Sciences

University of South Florida

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

We performed a double-blind randomized placebo-controlled pilot study to determine the efficacy of tegaserod (Zelnorm) in treating constipation in 15 patients with Parkinson's disease (PD). There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS).

Original language	English
Pages (from-to)	115-116
Number of pages	2
Journal	Movement Disorders
Volume	21
Issue number	1
DOIs	https://doi.org/10.1002/mds.20666
State	Published - Jan 2006

Scopus Subject Areas

Neurology
Clinical Neurology

Keywords

Constipation
Parkinson's disease
Tegaserod
Zelnorm

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10.1002/mds.20666

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abstract = "We performed a double-blind randomized placebo-controlled pilot study to determine the efficacy of tegaserod (Zelnorm) in treating constipation in 15 patients with Parkinson's disease (PD). There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS).",

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AB - We performed a double-blind randomized placebo-controlled pilot study to determine the efficacy of tegaserod (Zelnorm) in treating constipation in 15 patients with Parkinson's disease (PD). There was a trend for improvement in the Subject's Global Assessment (SGA) of satisfaction with bowel habits (NS) and the total SGA (including abdominal discomfort, bothersome constipation, and satisfaction; NS).

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KW - Parkinson's disease

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Tegaserod (Zelnorm) for the treatment of constipation in Parkinson's disease

Abstract

Scopus Subject Areas

Keywords

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