Abstract
The appropriateness of a one-sided alternative hypothesis rather than the more conservative, boiler-plate, two-sided hypothesis is discussed and examples provided. It is concluded that confirmatory efficacy clinical trials of pharmaceutical compounds should always be viewed within the one-sided alternative hypothesis testing framework.
| Original language | American English |
|---|---|
| Journal | Journal of Clinical Epidemiology |
| Volume | 42 |
| DOIs | |
| State | Published - 1989 |
Disciplines
- Public Health
- Biostatistics
Keywords
- Alternative hypothesis
- One-sided
- Two-sided