The reliability of 2,3,7,8-tetrachlorodibenzo-p-dioxin and toxicity equivalence measurements in Missouri residents

B. N. Shadel; Gregory Evans; Daryl W. Roberts

doi:10.1016/s0045-6535(99)00357-4

The reliability of 2,3,7,8-tetrachlorodibenzo-p-dioxin and toxicity equivalence measurements in Missouri residents

B. N. Shadel
, Gregory Evans
, Daryl W. Roberts

Health Policy & Community Health

Saint Louis University
Missouri Department of Health

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

This study evaluates the reliability of serum measurements of 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) and toxicity equivalence (TEQ) in individuals with no prior exposure to TCDD or dioxin-like compounds above background levels. Reliability was measured over three time-periods in the same individuals. TCDD and TEQ were measured in 127 and 128 participants. The values declined during the testing periods. Reliability coefficients for TCDD was 0.69 and for TEQ 0.91 but increased to 0.79 and 0.92, respectively, after removal of three outlying cases. Study results show good reliability over 22 months suggesting a consistency in the uptake and excretion of TCDD and other dioxin-like compounds. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	1089-1094
Number of pages	6
Journal	Chemosphere
Volume	40
Issue number	9-11
DOIs	https://doi.org/10.1016/s0045-6535(99)00357-4
State	Published - May 1 2000

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Scopus Subject Areas

Environmental Engineering
Environmental Chemistry
General Chemistry
Pollution
Health, Toxicology and Mutagenesis

Keywords

2,3,7,8,-Tetrachlorodibenzo-p- dioxin
Dioxin
Emissions
Equivalence
Exposure study
Incinerator
PCDD
TCDD
TEQ
Toxicity

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10.1016/s0045-6535(99)00357-4

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title = "The reliability of 2,3,7,8-tetrachlorodibenzo-p-dioxin and toxicity equivalence measurements in Missouri residents",

abstract = "This study evaluates the reliability of serum measurements of 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) and toxicity equivalence (TEQ) in individuals with no prior exposure to TCDD or dioxin-like compounds above background levels. Reliability was measured over three time-periods in the same individuals. TCDD and TEQ were measured in 127 and 128 participants. The values declined during the testing periods. Reliability coefficients for TCDD was 0.69 and for TEQ 0.91 but increased to 0.79 and 0.92, respectively, after removal of three outlying cases. Study results show good reliability over 22 months suggesting a consistency in the uptake and excretion of TCDD and other dioxin-like compounds. (C) 2000 Elsevier Science Ltd.",

keywords = "2,3,7,8,-Tetrachlorodibenzo-p- dioxin, Dioxin, Emissions, Equivalence, Exposure study, Incinerator, PCDD, TCDD, TEQ, Toxicity",

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T1 - The reliability of 2,3,7,8-tetrachlorodibenzo-p-dioxin and toxicity equivalence measurements in Missouri residents

AU - Shadel, B. N.

AU - Evans, Gregory

AU - Roberts, Daryl W.

PY - 2000/5/1

Y1 - 2000/5/1

N2 - This study evaluates the reliability of serum measurements of 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) and toxicity equivalence (TEQ) in individuals with no prior exposure to TCDD or dioxin-like compounds above background levels. Reliability was measured over three time-periods in the same individuals. TCDD and TEQ were measured in 127 and 128 participants. The values declined during the testing periods. Reliability coefficients for TCDD was 0.69 and for TEQ 0.91 but increased to 0.79 and 0.92, respectively, after removal of three outlying cases. Study results show good reliability over 22 months suggesting a consistency in the uptake and excretion of TCDD and other dioxin-like compounds. (C) 2000 Elsevier Science Ltd.

AB - This study evaluates the reliability of serum measurements of 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) and toxicity equivalence (TEQ) in individuals with no prior exposure to TCDD or dioxin-like compounds above background levels. Reliability was measured over three time-periods in the same individuals. TCDD and TEQ were measured in 127 and 128 participants. The values declined during the testing periods. Reliability coefficients for TCDD was 0.69 and for TEQ 0.91 but increased to 0.79 and 0.92, respectively, after removal of three outlying cases. Study results show good reliability over 22 months suggesting a consistency in the uptake and excretion of TCDD and other dioxin-like compounds. (C) 2000 Elsevier Science Ltd.

KW - 2,3,7,8,-Tetrachlorodibenzo-p- dioxin

KW - Dioxin

KW - Emissions

KW - Equivalence

KW - Exposure study

KW - Incinerator

KW - PCDD

KW - TCDD

KW - TEQ

KW - Toxicity

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UR - https://www.scopus.com/pages/publications/0034000901

U2 - 10.1016/s0045-6535(99)00357-4

DO - 10.1016/s0045-6535(99)00357-4

M3 - Article

SN - 0045-6535

VL - 40

SP - 1089

EP - 1094

JO - Chemosphere

JF - Chemosphere

IS - 9-11

ER -

The reliability of 2,3,7,8-tetrachlorodibenzo-p-dioxin and toxicity equivalence measurements in Missouri residents

Abstract

UN SDGs

Scopus Subject Areas

Keywords

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