The Reliability of 2,3,7,8-Tetrochlorodibenzo-p-Dioxin and Toxicity Equivalence Measurements in Missouri Residents

B. N. Shadel; Gregory Evans; Daryl W. Roberts

doi:10.1016/S0045-6535(99)00357-4

The Reliability of 2,3,7,8-Tetrochlorodibenzo-p-Dioxin and Toxicity Equivalence Measurements in Missouri Residents

B. N. Shadel, Gregory Evans, Daryl W. Roberts

Emeriti, Retired, & In Memoriam (JPHCOPH)

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

This study evaluates the reliability of serum measurements of 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) and toxicity equivalence (TEQ) in individuals with no prior exposure to TCDD or dioxin-like compounds above background levels. Reliability was measured over three time-periods in the same individuals. TCDD and TEQ were measured in 127 and 128 participants. The values declined during the testing periods. Reliability coefficients for TCDD was 0.69 and for TEQ 0.91 but increased to 0.79 and 0.92, respectively, after removal of three outlying cases. Study results show good reliability over 22 months suggesting a consistency in the uptake and excretion of TCDD and other dioxin-like compounds.

Original language	American English
Journal	Chemosphere
Volume	40
DOIs	https://doi.org/10.1016/S0045-6535(99)00357-4
State	Published - May 2000

Keywords

Measurements
Missouri
Reliability
Residents
Tetrochlorodibenzo-p-Dioxin

DC Disciplines

Public Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S0045-6535(99)00357-4License: Unspecified

Cite this

@article{83b31620e05c4f17b5510eee1cee0e43,

title = "The Reliability of 2,3,7,8-Tetrochlorodibenzo-p-Dioxin and Toxicity Equivalence Measurements in Missouri Residents",

abstract = " This study evaluates the reliability of serum measurements of 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) and toxicity equivalence (TEQ) in individuals with no prior exposure to TCDD or dioxin-like compounds above background levels. Reliability was measured over three time-periods in the same individuals. TCDD and TEQ were measured in 127 and 128 participants. The values declined during the testing periods. Reliability coefficients for TCDD was 0.69 and for TEQ 0.91 but increased to 0.79 and 0.92, respectively, after removal of three outlying cases. Study results show good reliability over 22 months suggesting a consistency in the uptake and excretion of TCDD and other dioxin-like compounds.",

keywords = "Measurements, Missouri, Reliability, Residents, Tetrochlorodibenzo-p-Dioxin",

author = "Shadel, {B. N.} and Gregory Evans and Roberts, {Daryl W.}",

year = "2000",

month = may,

doi = "10.1016/S0045-6535(99)00357-4",

language = "American English",

volume = "40",

journal = "Chemosphere",

issn = "0045-6535",

publisher = "Elsevier Ltd",

}

TY - JOUR

T1 - The Reliability of 2,3,7,8-Tetrochlorodibenzo-p-Dioxin and Toxicity Equivalence Measurements in Missouri Residents

AU - Shadel, B. N.

AU - Evans, Gregory

AU - Roberts, Daryl W.

PY - 2000/5

Y1 - 2000/5

N2 - This study evaluates the reliability of serum measurements of 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) and toxicity equivalence (TEQ) in individuals with no prior exposure to TCDD or dioxin-like compounds above background levels. Reliability was measured over three time-periods in the same individuals. TCDD and TEQ were measured in 127 and 128 participants. The values declined during the testing periods. Reliability coefficients for TCDD was 0.69 and for TEQ 0.91 but increased to 0.79 and 0.92, respectively, after removal of three outlying cases. Study results show good reliability over 22 months suggesting a consistency in the uptake and excretion of TCDD and other dioxin-like compounds.

AB - This study evaluates the reliability of serum measurements of 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) and toxicity equivalence (TEQ) in individuals with no prior exposure to TCDD or dioxin-like compounds above background levels. Reliability was measured over three time-periods in the same individuals. TCDD and TEQ were measured in 127 and 128 participants. The values declined during the testing periods. Reliability coefficients for TCDD was 0.69 and for TEQ 0.91 but increased to 0.79 and 0.92, respectively, after removal of three outlying cases. Study results show good reliability over 22 months suggesting a consistency in the uptake and excretion of TCDD and other dioxin-like compounds.

KW - Measurements

KW - Missouri

KW - Reliability

KW - Residents

KW - Tetrochlorodibenzo-p-Dioxin

UR - https://doi.org/10.1016/S0045-6535(99)00357-4

U2 - 10.1016/S0045-6535(99)00357-4

DO - 10.1016/S0045-6535(99)00357-4

M3 - Article

SN - 0045-6535

VL - 40

JO - Chemosphere

JF - Chemosphere

ER -

The Reliability of 2,3,7,8-Tetrochlorodibenzo-p-Dioxin and Toxicity Equivalence Measurements in Missouri Residents

Abstract

Keywords

DC Disciplines

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this