TY - JOUR
T1 - Thermally enhanced near-infrared luminescence in CaSc2O4
T2 - Yb3+/Nd3+ nanorods for temperature sensing and photothermal conversion
AU - Xiang, Guotao
AU - Yang, Menglin
AU - Liu, Zhen
AU - Wang, Yongjie
AU - Jiang, Sha
AU - Li, Li
AU - Zhou, Xianju
AU - Ma, Li
AU - Wang, Xiaojun
AU - Zhang, Jiahua
N1 - Publisher Copyright:
© 2022 Elsevier Ltd and Techna Group S.r.l.
PY - 2022/8/15
Y1 - 2022/8/15
N2 - Non-invasive photothermal therapy (PTT) is proposed as a powerful method for cancer treatment, in which a precise temperature monitoring is strongly recommended during the photothermal conversion process to prevent the damage of normal cells. Herein, ultra-sensitive optical thermometry with excellent resolution and outstanding light-to-heat conversion are simultaneously realized in CaSc2O4: Yb3+/Nd3+ nanorods. The temperature sensing of the nanorods is accomplished through fluorescence intensity ratio (FIR) technology based on the thermally coupled levels (TCLs) Nd3+: 4Fj (j = 7/2, 5/2, 3/2), of which the obtained absolute sensitivity is about 6.5 times larger than the optimal value of TCLs-based thermometers reported previously. Meanwhile, an intense thermal enhancement of Nd3+: 4Fj (j = 7/2, 5/2, 3/2) → 4I9/2 transition is found due to the efficiency improvement of phonon-assisted energy transfer process between Yb3+ ions and Nd3+ ions. The penetrability of the near-infrared light emitting by Nd3+ ions is determined by a simple ex vivo experiment, indicating a penetration depth of 8 mm in the biological tissues with negligible effect on FIR values. Beyond that, the nanorods show remarkable photothermal conversion capacity under the excitation of 980 nm wavelength. The properties mentioned above show enormous potentiality of the present nanorods for PTT along with a real-time temperature sensing.
AB - Non-invasive photothermal therapy (PTT) is proposed as a powerful method for cancer treatment, in which a precise temperature monitoring is strongly recommended during the photothermal conversion process to prevent the damage of normal cells. Herein, ultra-sensitive optical thermometry with excellent resolution and outstanding light-to-heat conversion are simultaneously realized in CaSc2O4: Yb3+/Nd3+ nanorods. The temperature sensing of the nanorods is accomplished through fluorescence intensity ratio (FIR) technology based on the thermally coupled levels (TCLs) Nd3+: 4Fj (j = 7/2, 5/2, 3/2), of which the obtained absolute sensitivity is about 6.5 times larger than the optimal value of TCLs-based thermometers reported previously. Meanwhile, an intense thermal enhancement of Nd3+: 4Fj (j = 7/2, 5/2, 3/2) → 4I9/2 transition is found due to the efficiency improvement of phonon-assisted energy transfer process between Yb3+ ions and Nd3+ ions. The penetrability of the near-infrared light emitting by Nd3+ ions is determined by a simple ex vivo experiment, indicating a penetration depth of 8 mm in the biological tissues with negligible effect on FIR values. Beyond that, the nanorods show remarkable photothermal conversion capacity under the excitation of 980 nm wavelength. The properties mentioned above show enormous potentiality of the present nanorods for PTT along with a real-time temperature sensing.
KW - Energy transfer
KW - Nanorod
KW - Optical thermometry
KW - Photothermal conversion
KW - Thermal enhancement
UR - http://www.scopus.com/inward/record.url?scp=85130383795&partnerID=8YFLogxK
U2 - 10.1016/j.ceramint.2022.04.337
DO - 10.1016/j.ceramint.2022.04.337
M3 - Article
AN - SCOPUS:85130383795
SN - 0272-8842
VL - 48
SP - 23436
EP - 23443
JO - Ceramics International
JF - Ceramics International
IS - 16
ER -