Time-to-Event Endpoint Methods in Antibiotic Trials

Karl E. Peace

Time-to-Event Endpoint Methods in Antibiotic Trials

Biostatistics, Epidemiology & Environmental Health Sciences

Research output: Contribution to book or proceeding › Chapter

Abstract

Two efficacy endpoints of primary interest in the clinical development of antibiotic drugs for the treatment of infections are microbiological cure and clinical cure. Microbiological cure is typically defined as eradication of the infecting pathogen by the end of treatment and at the posttreatment follow-up visit. Similarly, clinical cure is defined as complete abatement of signs and symptoms of the infection by the end of treatment and at the posttreatment follow-up visit.

Original language	American English
Title of host publication	Design and Analysis of Clinical Trials with Time-to-Event Endpoints
State	Published - Apr 23 2009

Disciplines

Public Health
Biostatistics
Environmental Public Health
Epidemiology

Keywords

Antibiotic trials
Endpoint methods
Time-to-event

Access to Document

https://www.taylorfrancis.com/books/e/9781420066401/chapters/10.1201%2F9781420066401-17

Cite this

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M3 - Chapter

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ER -

Time-to-Event Endpoint Methods in Antibiotic Trials

Abstract

Disciplines

Keywords

Access to Document

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