Time-to-event endpoint methods in antibiotic trials

Karl E. Peace

Time-to-event endpoint methods in antibiotic trials

Karl E. Peace

Biostatistics, Epidemiology & Environmental Health Sciences

Research output: Contribution to book or proceeding › Chapter › peer-review

Abstract

Two efficacy endpoints of primary interest in the clinical development of antibiotic drugs for the treatment of infections are microbiological cure and clinical cure. Microbiological cure is typically defined as eradication of the infecting pathogen by the end of treatment and at the posttreatment follow-up visit. Similarly, clinical cure is defined as complete abatement of signs and symptoms of the infection by the end of treatment and at the posttreatment follow-up visit.

Original language	English
Title of host publication	Design and Analysis of Clinical Trials with Time-to-Event Endpoints
Publisher	CRC Press
Pages	293-303
Number of pages	11
ISBN (Electronic)	9781420066401
ISBN (Print)	9781420066395
State	Published - Jan 1 2009

Scopus Subject Areas

General Mathematics
General Medicine
General Pharmacology, Toxicology and Pharmaceutics

Cite this

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Time-to-event endpoint methods in antibiotic trials

Abstract

Scopus Subject Areas

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