Transmission biology, host associations, distribution and molecular diagnostics of neorickettsia

Vasyl V. Tkach, Stephen E. Greiman

Research output: Contribution to book or proceedingChapterpeer-review

3 Scopus citations

Abstract

The genus Neorickettsia includes a small number of obligate intracellular rickettsial bacteria normally endosymbiotic within all stages of digenean complex life cycles, where they are maintained through vertical transmission. Under some circumstances Neorickettsia may also be transmitted horizontally by digenean parasites to their vertebrate definitive hosts where they may infect macrophages and other cell types and cause diseases, in some cases severe. This chapter briefly discusses the history of research on Neorickettsia, their phylogenetic interrelationships, transmission biology of different species and species-level genetic lineages within the genus, associations among Neorickettsia and their digenean and vertebrate hosts, geographic distribution, and PCR-based molecular diagnostics and identification of Neorickettsia.

Original languageEnglish
Title of host publicationRickettsiales
Subtitle of host publicationBiology, Molecular Biology, Epidemiology, and Vaccine Development
PublisherSpringer International Publishing
Pages295-325
Number of pages31
ISBN (Electronic)9783319468594
ISBN (Print)9783319468570
DOIs
StatePublished - Jan 1 2016

Keywords

  • Distribution
  • Host associations
  • Molecular diagnostics
  • Neorickettsia
  • Potomac horse fever
  • Salmon poisoning of dogs
  • Sennetsu fever
  • Transmission

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