Triflic acid controlled successive annelation of aromatic sulfonamides: an efficient one-pot synthesis of N-sulfonyl pyrroles, indoles and carbazoles

Abid Shaikh, Liliana Teixeira, Béla Török

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53 Scopus citations
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Abstract

A novel one-pot synthesis of N-substituted heterocycles via successive cyclization/annelation starting from primary sulfonamides is described. This process directly leads to N-sulfonyl pyrroles, indoles and carbazoles. The selection of an appropriate reactant/triflic acid ratio successfully controls the formation of the desired product.

Original languageEnglish
Pages (from-to)4047-4050
Number of pages4
JournalTetrahedron Letters
Volume48
Issue number23
DOIs
StatePublished - Jun 4 2007

Scopus Subject Areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Keywords

  • Annelation
  • N-Heterocycles
  • Sulfonamides
  • Triflic acid

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